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Covid-19 Global Pandemic: Effects of SARS-CoV-2 on Different Organs of Human Body

Author(s): Muhammad Akram, Sabira Sultana, Hafsa Yousaf, Kainat Zafer, Bakhtawar Fatima, Naima Saeed, Fahad Said Khan, El Hadji Seydou Mbaye, G. Chelladurai
Abstract: The world is now facing an outbreak of a virus known as coronavirus, which began as an emergent pneumonia-like sickness in Wuhan, China, in December 2019 and has since spread swiftly around the globe. On March 11, 2020, WHO declared this situation as pandemic because it was rapidly spreading in different parts of Asia and Europe. Coronavirus disorder 2019 is due to a unique coronavirus. These viruses are RNA viruses that motive illnesses in vertebrates (birds and mammals). They motive moderate to severe infections of the respiratory tract. Coronaviruses are having different types of the main subgrouping include alpha, beta, gamma, and delta. The purpose of our study is to gain knowledge about the characteristics of the virus, prevalence of the disease, its severity and to identify effects of SARS-CoV-2 on different organs of the body and also the complications caused by this novel virus. From our study, we came to know that COVID mostly affects immuno-compromised patients. Analysis shows that aged adults males who have other diseases like heart diseases, diabetes, and diseases of the respiratory tract like COPD are more susceptible to SARS-CoV-2 in comparison to any other age group. COVID can affect different organs of the body but most commonly it affects the lungs of a patient. Because this virus has an infinity for the ACE2 receptors. Coronavirus attaches with ACE2 receptors of the host cells through its spike proteins and causes illness. Common symptoms include difficulty in breathing, a severe cough, high fever, chills fatigue. Less severe symptoms are trembling with chills, sore throat, headache is the common sense of taste or smell affected. It is a highly transmissible disease, spread very frequently from an infected person through the droplets inhalation produce during coughing and sneezing by the host. From the data, we can conclude that the recovery rate is much higher than the fatality rate. But we should have to take precautionary measures like the use of masks, frequently wash the hands, and follow the social distancing as this illness has no effective therapy.Keywords: Covid-19; Pandemic; Epidemiology; SARS-CoV-2; ACE2 receptors; immuno-compromised.
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